BGCs Overview

Using antiSMASH, we identified 14,592 biosynthetic gene clusters (BGCs) across 3,600 MAGs, encompassing seven major BGC classes. The most abundant classes were NRPS, constituting 25.36% of the total, followed by terpene-related at 21.25%.

The phyla rich in BGC included Myxococcota (~6 BGCs per genome) and Cyanobacteria (~5 BGCs per genome). BiG-SCAPE analysis clustered 6,165 BGCs into 1,761 gene cluster families and 8,427 singletons. Notably, the majority (99.3%) of biosynthetic gene clusters (BGCs) did not cluster with reference BGCs from the MIBiG database, and 99.5% remained unclustered with BGCs from the global metagenomic BGC Atlas. This suggests a vast reservoir of untapped BGC diversity in Greenlandic soils, highlighting their potential as a unique source of novel bioactive compounds.




BGC class distribution in Greenlandic soils
Distribution of BGC classes across Greenlandic MAGs

BGCs Browser

BGC Class Counts
ID NRPS Terpene Others RiPPs Other PKSs PKS-NRP Hybrids PKSI Saccharides

antiSMASH result

Please click on the ID in the table to view the corresponding antiSMASH results